Nixa is one of the fastest growing cities in Missouri. Located just 10 miles south of Springfield and 30 miles north of Branson on Highway 160, just 4 miles west of Highway 65. Between 1990 (4,706 persons) and 2000 (12,124), the city experienced a staggering growth rate of 157%. Current City estimates have the 2006 population at 17,000 persons, with population projections for 2010 suggesting the city will eclipse the 20,000 person mark. It is from this growth that the city anticipates and is planning for continued, sustainable development opportunities in the commercial, industrial and residential markets.

Nixa traces its origins back to the mid-1800s with the movement of farmers and traders into Southwest Missouri. The first settlers were farmers who chose to locate their homes along the wooded streams in the vicinity of what was to become Nixa. The growing community quickly became known as a stopover or crossroads site, as the community was about a half-day's ride with a team of horses from Springfield. It became a convenient stopping point for teamsters hauling supplies from Arkansas to Springfield and for those traveling to the lower James River and Arkansas.

One of Nixa's early civic leaders was Nicholas A. Inman, a blacksmith who moved from Tennessee in 1852. Inman established a partnership with Joe Weaver and opened a blacksmith shop in Ozark. Inman's family home site of 160 acres adjoins the present day corporate boundaries of Nixa.

As the community continued to grow and new settlers and businesses opened in this "crossroads" site, a post office was opened. At a town meeting held to select a name for the community and post office, it was suggested that the town be named after Inman because of his years of service to the community. Another suggestion that "nix" best described the community, as it was "nothing but a crossroads". An "a", Inman's middle initial, was added to "nix", arriving at the community's name - - Nixa. Nixa officially incorporated as a village on June 10, 1902.

Rapid residential growth has spurred new business development in Nixa. Many new retail, convenience and service-oriented businesses have located in the community since 1990 and expansion of existing industries is underway. Financial institutions have constructed new offices and two Springfield hospitals have opened satellite medical clinics to serve the growing Nixa population. Improved community facilities and services, such as the community center, police station and utility office, have been developed to serve the needs of the Nixa population into the 21st century.